Anti-CoAA

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-845A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A300-845A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Isoform 1 may function as a nuclear receptor coactivator, enhancing... more

Close menu

Product information "Anti-CoAA"

Protein function: Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1 (PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex (which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ (PubMed:25385835). Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway (PubMed:28712728). [The UniProt Consortium]

Keywords:	Anti-SIP, Anti-PSP2, Anti-RBM14, Anti-Paraspeckle protein 2, Anti-RNA-binding protein 14, Anti-SYT-interacting protein, Anti-RNA-binding motif protein 14, Anti-Synaptotagmin-interacting protein, Anti-RRM-containing coactivator activator/modulator
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-845A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, bovine, orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A300-845A-T maps to a region between residue 550 and 600 of human CoActivator Activator (RNA Binding Motif 14) using the numbering given in entry NP_006319.1 (GeneID 10432 ).
Format:	Antigen Affinity Purified