Anti-CNOT2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-562A-T	10 µl (10 µg)		-		2 - 8 business days*		165.00€
A302-562A	100 µl (100 µg)		-		2 - 8 business days*		586.00€

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Protein function: Component of the CCR4-NOT complex which is one of the major cellular mRNA... more

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Product information "Anti-CNOT2"

Protein function: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity. [The UniProt Consortium]

Keywords:	Anti-CNOT2, Anti-CDC36, Anti-HSPC131, Anti-CCR4-associated factor 2, Anti-CCR4-NOT transcription complex subunit 2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-562A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	synthetic peptide. The epitope recognized by A302-562A-T maps to a region between residue 490 and 540 of human CCR4-NOT transcription complex, subunit 2 using the numbering given in entry NP_055330.1 (GeneID 4848).
Format:	Antigen Affinity Purified