Anti-CLEC9A / DNGR1 (Dendritic Cell Marker), clone 8F9

Formulation: Purified Ab with BSA and Azide at 200ug/ml. Cellular Localization: Membrane. Positive Control: MCF-7 cells (FACS/IF). Chromosome Location: 12p13.2. Protein Function: Functions as an endocytic receptor on a small subset of myeloid cells specialized for the uptake and processing of material from dead cells. Recognizes filamentous form of actin in association with particular actin-binding domains of cytoskeletal proteins, including spectrin, exposed when cell membranes are damaged, and mediate the cross-presentation of dead-cell associated antigens in a Syk-dependent manner [The Uniprot Consortium]