Anti-CLASP2

Anti-CLASP2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-154A-T 10 µl (10 µg) -

3 - 9 business days*

131.00€
A302-154A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Microtubule plus-end tracking protein that promotes the stabilization of... more
Product information "Anti-CLASP2"
Protein function: Microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules (PubMed:26003921). Involved in the nucleation of noncentrosomal microtubules originating from the trans-Golgi network (TGN). Required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. May act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2 (PubMed:16824950). This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3-kinase signaling. Also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle (PubMed:16866869, PubMed:16914514). Acts as a mediator of ERBB2- dependent stabilization of microtubules at the cell cortex. [The UniProt Consortium]
Keywords: Anti-CLASP2, Anti-hOrbit2, Anti-KIAA0627, Anti-Protein Orbit homolog 2, Anti-CLIP-associating protein 2, Anti-Cytoplasmic linker-associated protein 2
Supplier: Bethyl Laboratories
Supplier-Nr: A302-154A

Properties

Application: IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A302-154A-T maps to a region between residue 1 and 50 of human cytoplasmic linker associated protein 2 using the numbering given in entry BAG11221.1 (GeneID 23122).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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