Anti-CIAPIN1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-809A-T	10 µl (2 µg)		-		2 - 8 business days*		165.00€
A302-809A	100 µl		-		2 - 8 business days*		586.00€

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Protein function: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery... more

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Product information "Anti-CIAPIN1"

Protein function: Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1 (PubMed:23596212). NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electrons for reduction during radical cofactor maturation in the catalytic small subunit. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells. [The UniProt Consortium]

Keywords:	Anti-CUA001, Anti-Anamorsin, Anti-Cytokine-induced apoptosis inhibitor 1, Anti-Fe-S cluster assembly protein DRE2 homolog
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-809A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine)
Immunogen:	synthetic peptide. The epitope recognized by A302-809A-T maps to a region between residue 262 and 312 of human Cytokine Induced Apoptosis Inhibitor 1 using the numbering given in entry NP_064709.2 (GeneID 57019).
Format:	Antigen Affinity Purified