Anti-CHM

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA003231.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA003231.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase)... more

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Product information "Anti-CHM"

Protein function: Substrate-binding subunit of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B composed of RABGGTA and RABGGTB, and remains bound to it after the geranylgeranyl transfer reaction. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins, this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 58% and to rat: 66%

Keywords:	Anti-CHM, Anti-REP1, Anti-REP-1, Anti-TCD protein, Anti-Rab escort protein 1, Anti-Choroideremia protein, Anti-Rab proteins geranylgeranyltransferase component A 1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA003231

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SRKDKTIQHV EVFCYASQDL HEDVEEAGAL QKNHALVTSA NSTEAADSAF LPTEDESLST MSCEMLTEQT PSSDPENALE VNGAEVTGEK ENHCDDKTCV PSTSAEDMSE NVPIAEDTTE QPKKNRITYS QIIKEG (ATA-APrEST74342)