Anti-CFL1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA053761.25 25 µl -

7 - 10 business days*

330.00€
ATA-HPA053761.100 100 µl -

7 - 10 business days*

463.00€
 
Protein function: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity... more
Product information "Anti-CFL1"
Protein function: Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity (PubMed:11812157). In conjunction with the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions via regulation of actin dynamics (PubMed:15580268). Required for the centralization of the mitotic spindle and symmetric division of zygotes. Plays a role in the regulation of cell morphology and cytoskeletal organization in epithelial cells (PubMed:21834987). Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
Keywords: Anti-CFL, Anti-p18, Anti-CFL1, Anti-Cofilin-1, Anti-18 kDa phosphoprotein, Anti-Cofilin, non-muscle isoform
Supplier: Atlas Antibodies
Supplier-Nr: HPA053761

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: HELQANCYEE VKDRCTLAEK LGGSAVISL (ATA-APrEST88661)

Database Information

KEGG ID : K05765 | Matching products
UniProt ID : P23528 | Matching products
Gene ID : GeneID 1072 | Matching products
Protein Atlas Nr. : ENSG00000172757

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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