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NEW
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG46377.50 | 50 µg | - | - |
6 - 14 business days* |
616.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong... more
Product information "Anti-CENTG1 / PIKE"
Protein function: GTPase-activating protein (GAP) for ARF1 and ARF5, which also shows strong GTPase activity. Isoform 1 participates in the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. It also regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. It seems to be oncogenic. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion. [The UniProt Consortium]
| Keywords: | Anti-PIKE, Anti-PIKE, Anti-AGAP2, Anti-GGAP2, Anti-GGAP2, Anti-CENTG1, Anti-AGAP-2, Anti-Cnt-g1, Anti-AGAP-2, Anti-Cnt-g1, Anti-Centaurin-gamma-1, Anti-Centaurin-gamma-1, Anti-Phosphatidylinositol 3-kinase enhancer, Anti-Phosphatidylinositol 3-kinase enha |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG46377 |
Properties
| Application: | IHC (paraffin), WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | A 15 amino acid synthetic peptide within the last 50 amino acids of human CENTG1 / PIKE |
| MW: | 125 kD |
| Format: | Purified |
Database Information
| KEGG ID : | K17848 | Matching products |
| UniProt ID : | Q99490 | Matching products |
| Gene ID : | GeneID 116986 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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