Anti-CENP-T

Anti-CENP-T
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-314A-T 10 µl (10 µg) -

6 - 10 business days*

131.00€
A302-314A 100 µl (100 µg) -

6 - 10 business days*

465.00€
 
Protein function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that... more
Product information "Anti-CENP-T"
Protein function: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Part of a nucleosome- associated complex that binds specifically to histone H3- containing nucleosomes at the centromere, as opposed to nucleosomes containing CENPA. Component of the heterotetrameric CENP-T-W-S-X complex that binds and supercoils DNA, and plays an important role in kinetochore assembly. CENPT has a fundamental role in kinetochore assembly and function. It is one of the inner kinetochore proteins, with most further proteins binding downstream. Required for normal chromosome organization and normal progress through mitosis. [The UniProt Consortium]
Keywords: Anti-CENPT, Anti-CENP-T, Anti-C16orf56, Anti-Centromere protein T, Anti-Interphase centromere complex protein 22
Supplier: Bethyl Laboratories
Supplier-Nr: A302-314A

Properties

Application: IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Rhesus Monkey, Gorilla, Chimpanzee, Crab-eating Macaque)
Immunogen: synthetic peptide. The epitope recognized by A302-314A-T maps to a region between residue 520 and 561 of human centromere protein T using the numbering given in entry NP_079358.3 (GeneID 80152).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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