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Track device being used
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| G-CAB20471.20 | 20 µl | - |
9 - 20 business days* |
103.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: May be involved in p53/TP53 mediated inhibition of cellular proliferation in... more
Product information "Anti-CDKN1A"
Protein function: May be involved in p53/TP53 mediated inhibition of cellular proliferation in response to DNA damage. Binds to and inhibits cyclin- dependent kinase activity, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression. Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1. At higher stoichiometric ratios, inhibits the kinase activity of the cyclin D- CDK4 complex (PubMed:25329316). Inhibits DNA synthesis by DNA polymerase delta by competing with POLD3 for PCNA binding. Plays an important role in controlling cell cycle progression and DNA damage-induced G2 arrest. [The UniProt Consortium]
| Keywords: | Anti-p21, Anti-Cip1, Anti-Cdkn1a, Anti-CDK-interacting protein 1, Anti-Cyclin-dependent kinase inhibitor 1, Anti-Melanoma differentiation-associated protein |
| Supplier: | Assay Genie |
| Supplier-Nr: | CAB20471 |
Properties
| Application: | WB |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | mouse, rat |
Database Information
| KEGG ID : | K06625 | Matching products |
| UniProt ID : | P39689 | Matching products |
| Gene ID : | GeneID 12575 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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