Anti-CDK5RAP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG45747.50	50 µg		-	-	10 - 15 business days*		501.00€

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Protein function: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative... more

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Product information "Anti-CDK5RAP2"

Protein function: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation. Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with EB1/MAPRE1, may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of the gamma-tubulin ring complex (gamma-TuRC) onto centrosomes (PubMed:26485573). In complex with PDE4DIP isoform 13/MMG8/SMYLE, MAPRE1 and AKAP9, contributes to microtubules nucleation and extension from the centrosome to the cell periphery (PubMed:29162697). Required for the recruitment of AKAP9 to centrosomes (PubMed:29162697). Plays a role in neurogenesis. [The UniProt Consortium]

Keywords:	Anti-CEP215, Anti-CDK5RAP2, Anti-Centrosome-associated protein 215, Anti-Centrosome-associated protein 215, Anti-CDK5 activator-binding protein C48, Anti-CDK5 activator-binding protein C48, Anti-CDK5 regulatory subunit-associated protein 2, Anti-CDK5 regu
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG45747

Properties

Application:	ICC, IF, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant protein containing to human CDK5RAP2
MW:	215 kD
Format:	Affinity Purified