Anti-CDK5RAP2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A300-554A-T	10 µl (10 µg)		-		3 - 7 business days*		165.00€
A300-554A	100 µl (100 µg)		-		3 - 7 business days*		586.00€

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Protein function: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative... more

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Product information "Anti-CDK5RAP2"

Protein function: Potential regulator of CDK5 activity via its interaction with CDK5R1. Negative regulator of centriole disengagement (licensing) which maintains centriole engagement and cohesion. Involved in regulation of mitotic spindle orientation. Plays a role in the spindle checkpoint activation by acting as a transcriptional regulator of both BUBR1 and MAD2 promoter. Together with MAPRE1, it may promote microtubule polymerization, bundle formation, growth and dynamics at the plus ends. Regulates centrosomal maturation by recruitment of a gamma- tubulin ring complex onto centrosomes (PubMed:26485573). [The UniProt Consortium]

Keywords:	Anti-CEP215, Anti-CDK5RAP2, Anti-Centrosome-associated protein 215, Anti-CDK5 activator-binding protein C48, Anti-CDK5 regulatory subunit-associated protein 2
Supplier:	Bethyl Laboratories
Supplier-Nr:	A300-554A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: chimpanzee)
Immunogen:	synthetic peptide. The epitope recognized by A300-554A-T maps to a region between residues 900 and 950 of human CDK5 Regulatory Subunit Associated Protein 2 using the numbering given in entry NP_060719.4 (GeneID 55755).
Format:	Antigen Affinity Purified