Anti-CDK5R1 / p35

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG66698.100	100 µg		-	-	6 - 14 business days*		616.00€

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Protein function: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required... more

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Product information "Anti-CDK5R1 / p35"

Protein function: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. [The UniProt Consortium]

Keywords:	Anti-CDK5R, Anti-CDK5R1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG66698

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat (Expected: mouse)
Immunogen:	Synthetic peptide within aa. 30-110 of Human CDK5R1 / p35
MW:	34 kD
Format:	Antigen Affinity Purified