Anti-CDK5R1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA000252.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA000252.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required... more

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Product information "Anti-CDK5R1"

Protein function: p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-CDK5R, Anti-CDK5R1
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA000252

Properties

Application:	ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: FITPANVVFL YMLCRDVISS EVGSDHELQA VLLTCLYLSY SYMGNEISYP LKPFLVESCK EAFWDRCLSV INLMSSKMLQ INADPHYFTQ VFSDLKNESG QEDK (ATA-APrEST90525)