Anti-CDK3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA007420.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA007420.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Serine/threonine-protein kinase that plays a critical role in the control of... more

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Product information "Anti-CDK3"

Protein function: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 49% and to rat: 49%

Keywords:	Anti-CDK3, Anti-CDKN3, EC=2.7.11.22, Anti-Cyclin-dependent kinase 3, Anti-Cell division protein kinase 3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA007420

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: PSEDTWPGVT QLPDYKGSFP KWTRKGLEEI VPNLEPEGRD LLMQLLQYDP SQRITAKTAL AHPYFSSPEP SPAARQYVLQ RFRH (ATA-APrEST71411)