Anti-CDK14 / PFTK1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG40790.100	100 µl		-	-	6 - 14 business days*		584.00€

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Protein function: Serine/threonine-protein kinase involved in the control of the eukaryotic cell... more

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Product information "Anti-CDK14 / PFTK1"

Protein function: Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. [The UniProt Consortium]

Keywords:	Anti-CDK14, Anti-KIAA0834, Anti-hPFTAIRE1, EC=2.7.11.22, Anti-Cyclin-dependent kinase 14, Anti-Cell division protein kinase 14, Anti-Serine/threonine-protein kinase PFTAIRE-1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG40790

Properties

Application:	IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rabbit)
Immunogen:	KLH-conjugated synthetic peptide corresponding to aa. 1-30 of Human CDK14 / PFTK1
MW:	53 kD
Format:	Purified