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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2566-01D.100 | 100 µg | - | - |
3 - 19 business days* |
675.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
CDCP1(CUB-domain containing protein 1, also CD318 and SIMA135) is a novel, 135kD cell surface... more
Product information "Anti-CDCP1, isoform 1, CT (CUB domain containing protein 1, CD318, Membrane glycoprotein gp140, SIMA"
CDCP1(CUB-domain containing protein 1, also CD318 and SIMA135) is a novel, 135kD cell surface glycoprotein that is found on tumor, stem cells, keratinocytes and colonic epithelial cells. It is reported that this protein is overexpressed in colon and lung cancers. It is a type I transmembrane (TM) protein that is involved with cell adhesion. Mouse CDCP1 is synthesized as an 833 amino acid (aa) precursor. It contains an extracellular region with three CUB domains (aa30-667) and a phosphotyrosine site at Tyr731. When unligated, CDCP1 can be proteolytically cleaved between aa270-300. This generates an 80kD TM protein that may be missing the N-terminal CUB domain (aa 221-350). Over aa25-667, mouse CDCP1 is 83% and 92% aa identical to human and rat CDCP1, respectively. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32000, Western Blot: 1-3ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-CUB domain-containing protein 1, Anti-Subtractive immunization M plus HEp3-associated 135 kDa protein |
Supplier: | United States Biological |
Supplier-Nr: | C2566-01D |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human |
Immunogen: | Synthetic peptide corresponding to C-PLLNTQEPMEPAE, from the C Terminus of human CDCP1 (NP_073753.3). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06732 | Matching products |
UniProt ID : | Q9H5V8 | Matching products |
Gene ID | GeneID 64866 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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