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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ABS-KC-31682.50 | 50 µl | - | - |
Request delivery time estimate |
206.00€
|
||
| ABS-KC-31682.100 | 100 µl | - | - |
Request delivery time estimate |
295.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Serine/threonine-protein kinase which is an important downstream effector of... more
Product information "Anti-CDC42BPA"
Protein function: Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration (PubMed:15723050, PubMed:9418861, PubMed:9092543). Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2 (PubMed:21457715). In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration (PubMed:18854160). Phosphorylates: PPP1R12A, LIMK1 and LIMK2 (PubMed:11340065, PubMed:11399775). May play a role in TFRC-mediated iron uptake (PubMed:20188707). In concert with FAM89B/LRAP25 mediates the targeting of LIMK1 to the lamellipodium resulting in its activation and subsequent phosphorylation of CFL1 which is important for lamellipodial F-actin regulation. Triggers the formation of an extrusion apical actin ring required for epithelial extrusion of apoptotic cells (PubMed:29162624). [The UniProt Consortium]
| Keywords: | Anti-KIAA0451, Anti-MRCK alpha, Anti-DMPK-like alpha, Anti-CDC42-binding protein kinase alpha, Anti-Serine/threonine-protein kinase MRCK alpha, Anti-Myotonic dystrophy protein kinase-like alpha |
| Supplier: | Absea |
| Supplier-Nr: | KC-31682 |
Properties
| Application: | WB |
| Antibody Type: | Monoclonal |
| Clone: | K24073_19H9 |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human, mouse |
| Immunogen: | recombinant human CDC42BPA |
| Format: | Solution |
Database Information
| KEGG ID : | K16307 | Matching products |
| UniProt ID : | Q5VT25 | Matching products |
| Gene ID : | GeneID 8476 | Matching products |
Handling & Safety
| Storage: | -20°C (avoid repeat freezing and thawing cycles) |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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