Anti-CDC14B

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA013312.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA013312.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Dual-specificity phosphatase involved in DNA damage response. Essential... more

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Product information "Anti-CDC14B"

Protein function: Dual-specificity phosphatase involved in DNA damage response. Essential regulator of the G2 DNA damage checkpoint: following DNA damage, translocates to the nucleus and dephosphorylates FZR1/CDH1, a key activator of the anaphase promoting complex/cyclosome (APC/C). Dephosphorylates SIRT2 around early anaphase. Dephosphorylation of FZR1/CDH1 activates the APC/C, leading to the ubiquitination of PLK1, preventing entry into mitosis. Preferentially dephosphorylates proteins modified by proline-directed kinases. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 80% and to rat: 83%

Keywords:	Anti-CDC14B, EC=3.1.3.48, EC=3.1.3.16, Anti-CDC14 cell division cycle 14 homolog B, Anti-Dual specificity protein phosphatase CDC14B
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA013312

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VENQDQQEPE PYSDDDEING VTQGDRSRAL (ATA-APrEST72285)