Anti-CD8a, clone HIT8a, Fluorescein Conjugated

Fluorescein conjugated CD8a Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD8a. Reactivity is observed against human CD8a, Marmoset, and chimpanzee. This clone recognizes the alpha chain of CD85. It does not block the binding of RPA-T8 antibody to CD8a. Cross reactivity with CD8a from other sources has not been tested. Anti-CD8a is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. Protein function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. CD8 alpha chains binds to class I MHC molecules alpha-3 domains. [The UniProt Consortium]