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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R31664 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cluster of Differentiation 86 (also known... more
Product information "Anti-CD86"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cluster of Differentiation 86 (also known as B7-2) is a protein expressed on antigen-presenting cells that provides costimulatory signals necessary for T cell activation and survival. The CD86 gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. The antigen presentation coactivators B7-1 and B7-2/CD86, which are important in other immune-mediated thyroid diseases, are important for lymphocytic infiltration and the immune response against thyroid carcinoma. Protein function: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation (PubMed:7527824). Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation. [The UniProt Consortium]
Keywords: | Anti-B70, Anti-BU63, Anti-CD86, Anti-FUN-1, Anti-CD28LG2, Anti-Activation B7-2 antigen, Anti-CTLA-4 counter-receptor B7.2, Anti-T-lymphocyte activation antigen CD86, CD86 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R31664 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | Human partial recombinant protein (AA 24-329) |
Format: | Purified |
Database Information
KEGG ID : | K05413 | Matching products |
UniProt ID : | P42081 | Matching products |
Gene ID | GeneID 942 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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