Anti-CD86

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG42635.100	100 µl		-	-	6 - 14 business days*		707.00€

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Protein function: Receptor involved in the costimulatory signal essential for T-lymphocyte... more

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Product information "Anti-CD86"

Protein function: Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation (PubMed:7527824). Also involved in the regulation of B cells function, plays a role in regulating the level of IgG(1) produced. Upon CD40 engagement, activates NF-kappa-B signaling pathway via phospholipase C and protein kinase C activation. [The UniProt Consortium]

Keywords:	Anti-B70, Anti-CD86, Anti-BU63, Anti-FUN-1, Anti-CD28LG2, Anti-Activation B7-2 antigen, Anti-CTLA-4 counter-receptor B7.2, Anti-T-lymphocyte activation antigen CD86
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG42635

Properties

Application:	IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	mouse (Expected: human, rat)
Immunogen:	Recombinant fusion protein corresponding to aa. 30-247 of Human CD86 (NP_787058.4)
MW:	38 kD
Format:	Affinity Purified