Anti-CD79b

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cluster of Differentiation 79b, is a human gene mapped to 17q23.3. The CD79b protein together with the relatedCD79aprotein, forms a dimer associated with membrane bound immunoglobulin in B-cells, thus forming the B-cell antigen receptor (BCR) which is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig). CD79b also enhances phosphorylation of CD79a, possibly by recruiting kinases, or by recruiting proteins which bind to CD79a and protect it from dephosphorylation. Protein function: Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. [The UniProt Consortium]