Anti-CD79a, clone JCB117

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55943.50	50 µg		-	-	6 - 14 business days*		608.00€

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Protein function: Required in cooperation with CD79B for initiation of the signal transduction... more

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Product information "Anti-CD79a, clone JCB117"

Protein function: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src- family tyrosine kinases. Represses BCR signaling during development of immature B-cells. [The UniProt Consortium]

Keywords:	Anti-IGA, Anti-CD79A, Anti-CD79a, Anti-Ig-alpha, Anti-MB-1 membrane glycoprotein, Anti-Surface IgM-associated protein, Anti-Membrane-bound immunoglobulin-associated protein, Anti-B-cell antigen receptor complex-associated protein alpha chain
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55943

Properties

Application:	FC, ICC, IF, IHC (paraffin)
Antibody Type:	Monoclonal
Clone:	JCB117
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Synthetic peptide around aa. 202-216 of Human CD79a (GTYQDVGSLNIADVQ)
Format:	Purified