Anti-CD79a, clone HM47 (APC)

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG54257.50	50 tests		-	-	6 - 14 business days*		554.00€

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Protein function: Required in cooperation with CD79B for initiation of the signal transduction... more

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Product information "Anti-CD79a, clone HM47 (APC)"

Protein function: Required in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src- family tyrosine kinases. Represses BCR signaling during development of immature B-cells. [The UniProt Consortium]

Keywords:	Anti-IGA, Anti-CD79a, Anti-CD79A, Anti-Ig-alpha, Anti-MB-1 membrane glycoprotein, Anti-Surface IgM-associated protein, Anti-Membrane-bound immunoglobulin-associated protein, Anti-B-cell antigen receptor complex-associated protein alpha chain
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG54257

Properties

Application:	FC, IP, WB, IHC (paraffin)
Antibody Type:	Monoclonal
Clone:	HM47
Conjugate:	APC
Host:	Mouse
Species reactivity:	human, primates, swine, mouse, rat, bovine, dog, horse, guinea pig, rabbit, chicken
Immunogen:	Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a