Anti-CD71 / Transferrin Receptor (FITC), clone 8D3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG23975.50	50 µg		-	-	6 - 14 business days*		534.00€

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Protein function: Cellular uptake of iron occurs via receptor-mediated endocytosis of... more

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Product information "Anti-CD71 / Transferrin Receptor (FITC), clone 8D3"

Protein function: Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Upon stimulation, positively regulates T and B cell proliferation through iron uptake (PubMed:26642240). [The UniProt Consortium]

Keywords:	Anti-TR, Anti-TfR, Anti-CD71, Anti-Trfr, Anti-TfR1, Anti-Tfrc, Anti-Transferrin receptor protein 1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG23975

Properties

Application:	FC
Antibody Type:	Monoclonal
Clone:	8D3
Conjugate:	FITC
Host:	Rat
Species reactivity:	mouse
Immunogen:	Mouse transformed endothelioma cell line
Format:	Purified