Anti-CD63 / LAMP-3, clone CDLA63-2R

Anti-CD63 / LAMP-3, clone CDLA63-2R
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7402SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. CD63 functions as cell surface receptor for TIMP1... more
Product information "Anti-CD63 / LAMP-3, clone CDLA63-2R"
1 mg/ml in 1X PBS, BSA free, sodium azide free. CD63 functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. [UniProt] Protein function: Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli. [The UniProt Consortium]
Keywords: Anti-CD63, Anti-MLA1, Anti-LAMP-3, Anti-OMA81H, Anti-Tspan-30, Anti-CD63 antigen, Anti-Granulophysin, Anti-Tetraspanin-30, Anti-Melanoma-associated antigen ME491, Anti-Ocular melanoma-associated antigen, Anti-Lysosomal-associated membrane protein 3, CD63
Supplier: NSJ Bioreagents
Supplier-Nr: V7402SAF

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: CDLA63-2R
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Full-length recombinant human protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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