Anti-CD59 (human), Unconjugated Clone MEM43 [Mouse]

Specificity: This antibody reacts with a PI-linked glycoprotein, molecular weight 18-20 kDa, found in all types of leucocytes including platelets., Format: Phosphate-buffered saline with 5 % BSA and 0.1 % sodium azide, Working Dilution: We recommend that each laboratory determine an optimum working titre for use in its particular application, Storage: Stable for 1 month at +2-8°C. For longer storage, freeze aliquots, Application Notes: Suitable for Flow Cytometry, IP, IHC paraffin Protein function: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. [The UniProt Consortium]