Anti-CD59

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-13133.20 20 µl -

7 - 16 business days*

71.00€
E-AB-13133.60 60 µl -

7 - 16 business days*

143.00€
E-AB-13133.120 120 µl -

7 - 16 business days*

238.00€
E-AB-13133.200 200 µl -

7 - 16 business days*

396.00€
 
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and... more
Product information "Anti-CD59"
This gene encodes a cell surface glycoprotein that regulates complement-mediated cell lysis, and it is involved in lymphocyte signal transduction. This protein is a potent inhibitor of the complement membrane attack complex, whereby it binds complement C8 and/or C9 during the assembly of this complex, thereby inhibiting the incorporation of multiple copies of C9 into the complex, which is necessary for osmolytic pore formation. This protein also plays a role in signal transduction pathways in the activation of T cells. Mutations in this gene cause CD59 deficiency, a disease resulting in hemolytic anemia and thrombosis, and which causes cerebral infarction. Protein function: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. [The UniProt Consortium]
Keywords: Anti-MIRL, Anti-CD59, Anti-MIC11, Anti-MACIF, Anti-HRF20, Anti-MAC-IP, Anti-HRF-20, Anti-Protectin, Anti-1F5 antigen, Anti-MEM43 antigen, Anti-CD59 glycoprotein, Anti-MAC-inhibitory protein, Anti-20 kDa homologous restriction factor, CD59 Polyclonal Antib
Supplier: Elabscience
Supplier-Nr: E-AB-13133

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Synthetic peptide of human CD59
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-CD59"
Write a review
or to review a product.
Viewed