Anti-CD59, clone MACIF/629

Anti-CD59, clone MACIF/629
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3022IHC-7ML 7 ml - -

3 - 10 business days

541.00€
 
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. CD59 is... more
Product information "Anti-CD59, clone MACIF/629"
Prediluted in 1X PBS, 0.1 mg/ml BSA (US sourced), 0.05% sodium azide, *For IHC use only*. CD59 is a potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes. [UniProt] Protein function: Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. [The UniProt Consortium]
Keywords: Anti-CD59, Anti-MIRL, Anti-MACIF, Anti-HRF20, Anti-MIC11, Anti-HRF-20, Anti-MAC-IP, Anti-Protectin, Anti-1F5 antigen, Anti-MEM43 antigen, Anti-CD59 glycoprotein, Anti-MAC-inhibitory protein, Anti-Membrane inhibitor of reactive lysis, CD59 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3022IHC-7ML

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: MACIF/629
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant full-length human CD59 protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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