Anti-CD53, clone 63-5A3

Anti-CD53, clone 63-5A3
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3018-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3018-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 33-55kDa,... more
Product information "Anti-CD53, clone 63-5A3"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 33-55kDa, identified as CD53 (Workshop V, Code CD53.1). CD53 is expressed on monocytes, and macrophages, granulocytes, dendritic cells, osteoblasts and osteoclasts, NK cells, and on T- and B-cells from every stage of differentiation but is absent from platelets, erythrocytes, and non-haemopoietic cells. CD53 is a member of a family of tetraspan transmembrane proteins, including CD9, CD37, CD63, CD81, and CD82. It associates with integrins, MHC class II molecules, and a tyrosine phosphatase and plays a role in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. Defects of CD53 expression on neutrophils appear to be related with recurrent infectious diseases. Cross-linking CD53 using CD53 antibodies led to cytoplasmic calcium fluxes in B cells, monocytes, and granulocytes and activation of the monocyte oxidative burst. Protein function: Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells. [The UniProt Consortium]
Keywords: Anti-CD53, Anti-MOX44, Anti-Tspan-25, Anti-Tetraspanin-25, Anti-Cell surface glycoprotein CD53, Anti-Leukocyte surface antigen CD53, CD53 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3018-20UG

Properties

Application: FA (activity), FC, IF
Antibody Type: Monoclonal
Clone: 63-5A3
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Sezary cells
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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