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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3018-20UG | 20 µg | - | - |
3 - 10 business days* |
332.00€
|
||
NSJ-V3018-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 33-55kDa,... more
Product information "Anti-CD53, clone 63-5A3"
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide. Recognizes a protein of 33-55kDa, identified as CD53 (Workshop V, Code CD53.1). CD53 is expressed on monocytes, and macrophages, granulocytes, dendritic cells, osteoblasts and osteoclasts, NK cells, and on T- and B-cells from every stage of differentiation but is absent from platelets, erythrocytes, and non-haemopoietic cells. CD53 is a member of a family of tetraspan transmembrane proteins, including CD9, CD37, CD63, CD81, and CD82. It associates with integrins, MHC class II molecules, and a tyrosine phosphatase and plays a role in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. Defects of CD53 expression on neutrophils appear to be related with recurrent infectious diseases. Cross-linking CD53 using CD53 antibodies led to cytoplasmic calcium fluxes in B cells, monocytes, and granulocytes and activation of the monocyte oxidative burst. Protein function: Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells. [The UniProt Consortium]
Keywords: | Anti-CD53, Anti-MOX44, Anti-Tspan-25, Anti-Tetraspanin-25, Anti-Cell surface glycoprotein CD53, Anti-Leukocyte surface antigen CD53, CD53 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3018 |
Properties
Application: | FA (activity), FC, IF |
Antibody Type: | Monoclonal |
Clone: | 63-5A3 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Sezary cells |
Format: | Purified |
Database Information
KEGG ID : | K06489 | Matching products |
UniProt ID : | P19397 | Matching products |
Gene ID | GeneID 963 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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