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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-V3019SAF-100UG | 100 µg | - | - |
3 - 10 business days* |
752.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 33-55kDa, identified... more
Product information "Anti-CD53, clone 161-2"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 33-55kDa, identified as CD53 (Workshop VI, Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This mAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1). Protein function: Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells. [The UniProt Consortium]
Keywords: | Anti-CD53, Anti-MOX44, Anti-Tspan-25, Anti-Tetraspanin-25, Anti-Cell surface glycoprotein CD53, Anti-Leukocyte surface antigen CD53, CD53 Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | V3019SAF |
Properties
Application: | FA (activity), FC, IF |
Antibody Type: | Monoclonal |
Clone: | 161-2 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Stimulated human leukocytes |
Format: | Purified |
Database Information
KEGG ID : | K06489 | Matching products |
UniProt ID : | P19397 | Matching products |
Gene ID | GeneID 963 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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