Anti-CD53, clone 161-2

Anti-CD53, clone 161-2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3019SAF-100UG 100 µg - -

3 - 10 business days

1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 33-55kDa, identified... more
Product information "Anti-CD53, clone 161-2"
1 mg/ml in sterile PBS, BSA free, sodium azide free. Recognizes a protein of 33-55kDa, identified as CD53 (Workshop VI, Code N-L033). It is expressed on monocytes and macrophages, dendritic cells, osteoblasts and osteoclasts, and on T and B cells from every stage of differentiation but is absent from platelets, red blood cells. CD53 appears to be the marker with widest reactivity as well as the marker with the strictest specificity to hematopoietic cells. CD53 is a type III membrane with both termini in the cytoplasm and two loops in the extracellular environment. This molecule, in common with other members of tetraspan family, is involved in cellular activation as part of a signal transduction complex involving other membrane glycoproteins. CD53 crosslinking induces calcium flux on human monocyte and B cells. Cross-linking of CD53 promotes activation of resting human B-lymphocytes. This mAb recognizes CD53 transfected cells and partially inhibits T-cell proliferation induced by CD3 antibody (clone: UCHT1). Protein function: Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells. [The UniProt Consortium]
Keywords: Anti-CD53, Anti-MOX44, Anti-Tspan-25, Anti-Tetraspanin-25, Anti-Cell surface glycoprotein CD53, Anti-Leukocyte surface antigen CD53, CD53 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3019SAF-100UG


Application: FA (activity), FC, IF
Antibody Type: Monoclonal
Clone: 161-2
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Stimulated human leukocytes
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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