Anti-CD50/ICAM-3 Monoclonal Recombinant Antibody

Anti-CD50/ICAM-3 Monoclonal Recombinant Antibody
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AN300042P.100 100 µl -

7 - 16 business days*

462.00€
 
CD50 is a 120-140 kD type I membrane protein also known as intercellular adhesion molecule 3... more
Product information "Anti-CD50/ICAM-3 Monoclonal Recombinant Antibody"
CD50 is a 120-140 kD type I membrane protein also known as intercellular adhesion molecule 3 (ICAM-3). It is broadly expressed on leukocytes, endothelial cells, and Langerhans cells. CD50 is a member of the Ig superfamily. It provides costimulatory signal for T cells and regulates cell adhesion through interaction with LFA-1 (CD11a/CD18, alphaL/beta2) integrin. Protein function: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2) (PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha- L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed:23775590). [The UniProt Consortium]
Keywords: CD50, ICAM3, CDw50, ICAM-R, ICAM-3, Intercellular adhesion molecule 3, Recombinant CD50/ICAM-3 Monoclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AN300042P

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: 1F9
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Human CD50 / ICAM-3 protein
Format: Purified

Handling & Safety

Storage: +4°C (avoid repeat freezing and thawing cycles)
Shipping: +4°C (International: +4°C)
Signal Word: Warning
GHS Hazard Pictograms:
H Phrases: H317
P Phrases: P261, P272, P280, P302+352, P333+313
Caution
Our products are for laboratory research use only: Not for administration to humans!
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