Anti-CD46, clone 169-1-E4.3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG56050.50	50 µg		-	-	6 - 14 business days*		608.00€

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Protein function: Acts as a cofactor for complement factor I, a serine protease which protects... more

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Product information "Anti-CD46, clone 169-1-E4.3"

Protein function: Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement- mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T- cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. [The UniProt Consortium]

Keywords:	Anti-MCP, Anti-TLX, Anti-CD46, Anti-Membrane cofactor protein, Anti-Trophoblast leukocyte common antigen
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG56050

Properties

Application:	FC, ICC, IF
Antibody Type:	Monoclonal
Clone:	169-1-E4.3
Conjugate:	No
Host:	Mouse
Species reactivity:	human, baboon
Immunogen:	Stimulated Human leukocytes
Format:	Purified