Anti-CD45

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-376A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A304-376A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the... more

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Product information "Anti-CD45"

Protein function: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity. [The UniProt Consortium]

Keywords:	Anti-L-CA, Anti-CD45, Anti-T200, Anti-PTPRC, EC=3.1.3.48, Anti-Leukocyte common antigen, Anti-Receptor-type tyrosine-protein phosphatase C
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-376A

Properties

Application:	WB, IP, IHC, ICC-IF
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, cyanobacteria, root node of taxonomy, black-headed night monkey, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A304-376A-T maps to a region between residue 1254 to 1304 of human CD45 Molecule using the numbering given in entry P08575.2 (GeneID 5788).
Format:	Antigen Affinity Purified