Anti-CD45

Anti-CD45
Item number Size Datasheet Manual SDS Delivery time Quantity Price
030058.100 100 µl - -

3 - 19 business days*

477.00€
 
CD45, also known as TPRC(protein tyrosine phosphatase, receptor type, C). The protein encoded by... more
Product information "Anti-CD45"
CD45, also known as TPRC(protein tyrosine phosphatase, receptor type, C). The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus belongs to receptor type PTP. This gene is specifically expressed in hematopoietic cells. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Four alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. Applications: Western Bloting: 1:500-1:2000., Immunohistochemistry: 1:200-1:1000., ELISA: Suggested dilution 1:10000., Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-T200, Anti-L-CA, Anti-CD45, Anti-PTPRC, EC=3.1.3.48, Anti-Leukocyte common antigen, Anti-Receptor-type tyrosine-protein phosphatase C
Supplier: United States Biological
Supplier-Nr: 030058

Properties

Application: ELISA, IHC, WB
Antibody Type: Monoclonal
Clone: 13B136
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Purified recombinant fragment of CD45 expressed in E. coli.

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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