Anti-CD44 / HCAM, clone HCM15-2R

Anti-CD44 / HCAM, clone HCM15-2R
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V7303SAF-100UG 100 µg - -

3 - 10 business days*

752.00€
 
1 mg/ml in 1X PBS, BSA free, sodium azide free. Receptor for hyaluronic acid (HA). Mediates... more
Product information "Anti-CD44 / HCAM, clone HCM15-2R"
1 mg/ml in 1X PBS, BSA free, sodium azide free. Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (By similarity). [UniProt] Protein function: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Receptor for LGALS9, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function. [The UniProt Consortium]
Keywords: Anti-LHR, Anti-CD44, Anti-CDw44, Anti-PGP-1, Anti-PGP-I, Anti-Epican, Anti-HUTCH-I, Anti-ECMR-III, Anti-CD44 antigen, Anti-Hermes antigen, Anti-Hyaluronate receptor, Anti-Phagocytic glycoprotein I, Anti-Phagocytic glycoprotein 1, CD44 Antibody / HCAM
Supplier: NSJ Bioreagents
Supplier-Nr: V7303SAF

Properties

Application: IHC (paraffin)
Antibody Type: Monoclonal
Clone: HCM15-2R
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Stimulated human leukocytes
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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