Anti-CD44 (Spectral Red), clone KM201

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG20799.50	50 µg		-	-	6 - 14 business days*		493.00€

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Protein function: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix... more

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Product information "Anti-CD44 (Spectral Red), clone KM201"

Protein function: Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Receptor for LGALS9, the interaction enhances binding of SMAD3 to the FOXP3 promoter, leading to up-regulation of FOXP3 expression and increased induced regulatory T (iTreg) cell stability and suppressive function (PubMed:25065622). [The UniProt Consortium]

Keywords:	Anti-Cd44, Anti-CD44, Anti-PGP-I, Anti-Ly-24, Anti-PGP-1, Anti-HUTCH-I, Anti-ECMR-III, Anti-CD44 antigen, Anti-Hermes antigen, Anti-Hyaluronate receptor, Anti-Lymphocyte antigen 24, Anti-Phagocytic glycoprotein 1, Anti-Phagocytic glycoprotein I
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG20799

Properties

Application:	FC, IHC (frozen), IHC (paraffin), ICC, IF, WB, BL
Antibody Type:	Monoclonal
Clone:	KM201
Conjugate:	Spectral Red
Host:	Rat
Species reactivity:	mouse
Immunogen:	(C57BL/6 x DBA/2)F1 mouse bone marrow-derived stromal clone BMS2