Cookie preferences
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the comfort when using this website, are used for direct advertising or to facilitate interaction with other websites and social networks, are only set with your consent.
Configuration
Technically required
These cookies are necessary for the basic functions of the shop.
"Allow all cookies" cookie
"Decline all cookies" cookie
CSRF token
Cookie preferences
Currency change
Customer-specific caching
FACT-Finder tracking
Individual prices
Selected shop
Session
Comfort functions
These cookies are used to make the shopping experience even more appealing, for example for the recognition of the visitor.
Note
Show the facebook fanpage in the right blod sidebar
Statistics & Tracking
Affiliate program
Conversion and usertracking via Google Tag Manager
Track device being used
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2395-20.100 | 100 µg | - | - |
3 - 19 business days* |
962.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Platelet glycoprotein Ib alpha chain (GPIb-alpha), also known as CD42b alpha, is a 145kD platelet... more
Product information "Anti-CD42b alpha (Glycoprotein Ib alpha, GPIba)"
Platelet glycoprotein Ib alpha chain (GPIb-alpha), also known as CD42b alpha, is a 145kD platelet type I transmembrane protein. It binds von Willebrand factor (VWF) and thrombin, and is part of the platelet GPIb-IX-V complex, which plays important roles in vascular biology, including hemostasis and thrombosis. GPIb-alpha is also a member of the family of proteins with leucine-rich repeats, which mediate protein-protein interactions. The 610 residue mature human GPIb-alpha contains a 489aa extracellular domain (ECD) (aa17-505) and a 100aa cytoplasmic region (aa527-626). Proteolytic cleavage of the GPIb-alpha ECD from platelet surface releases soluble GPIb-alpha (glycocalicin), which is found in plasma. The ECDs of human, mouse and canine GPIb-Alpha share approximately 50% aa sequence identity. Applications: Suitable for use in Flow Cytometry, Western Blot and ELISA. Other applications not tested. Recommended Dilution: Flow Cytometry: 25ug/ml, Add 10ul of diluted antibody to 1-2.5x10e5 cells in a total reaction volume no greater than 200ul. Tested using blood-derived CD41+ platelets., Western Blot: 0.1-0.2ug/ml, Detection limit under non-reducing and reducing conditions of rhGPIb-alpha is ~1ng/lane., ELISA: 0.5-1ug/ml, Detection limit of rhGPIb-alpha is ~5ng/well., Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-GP1BA |
Supplier: | United States Biological |
Supplier-Nr: | C2395-20 |
Properties
Application: | ELISA, FC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Sheep |
Species reactivity: | human |
Immunogen: | NS0-derived recombinant human rhGPIb-Alpha (aa17-505) Accession # P07359 |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06261 | Matching products |
UniProt ID : | P07359 | Matching products |
Gene ID | GeneID 2811 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
more
You will get a certificate here
Viewed