Anti-CD41, clone PM6/248

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG23040.100	100 µg		-	-	6 - 14 business days*		640.00€

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Protein function: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen,... more

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Product information "Anti-CD41, clone PM6/248"

Protein function: Integrin alpha-IIb/beta-3 is a receptor for fibronectin, fibrinogen, plasminogen, prothrombin, thrombospondin and vitronectin. It recognizes the sequence R-G-D in a wide array of ligands. It recognizes the sequence H-H-L-G-G-G-A-K-Q-A-G-D-V in fibrinogen gamma chain. Following activation integrin alpha- IIb/beta-3 brings about platelet/platelet interaction through binding of soluble fibrinogen. This step leads to rapid platelet aggregation which physically plugs ruptured endothelial cell surface. [The UniProt Consortium]

Keywords:	Anti-GP2B, Anti-ITGA2B
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG23040

Properties

Application:	FC
Antibody Type:	Monoclonal
Clone:	PM6/248
Conjugate:	No
Host:	Mouse
Species reactivity:	human, baboon
Immunogen:	Human platelet plasma membranes
Format:	Purified