Anti-CD36 (human), Unconjugated Clone TR9 [Mouse]

Specificity: Reacts with CD36 (GPIIIb), a 85 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes, Format: 20 mM Tris/HCl with 15 mM sodium azide, approx. pH 7.4, Working Dilution: We recommend that each laboratory determine an optimum working titre for use in its particular application, Storage: Store at +2-8°C. For longer storage, freeze aliquots, Application Notes: Suitable for Flow Cytometry Protein function: Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells (PubMed:12016218, PubMed:12519372, PubMed:21226579). Receptor for HDL, mediating selective uptake of cholesteryl ether and HDL-dependent cholesterol efflux (PubMed:26965621). Also facilitates the flux of free and esterified cholesterol between the cell surface and apoB-containing lipoproteins and modified lipoproteins, although less efficiently than HDL. May be involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (PubMed:12016218). [The UniProt Consortium]