Anti-CD36 (gpIIIb, gpIV), clone 0.N.107

CD36 (also known as platelet glycoprotein IV, OKM5-antigen, or platelet glycoprotein IIIb) acts as a receptor for thrombospondin (TSP), collagen, falciparum malaria parasitized erythrocytes, and sickle erythrocytes. It also functions as a scavenger receptor, mediating macrophage uptake of oxidized low density lipoprotein (LDL), and apoptotic polymorphonuclear leukocytes (PMN). CD36 plays a role in platelet aggregation, macrophage foam cell development, inflammation, and the tissue ischaemia observed in sickle cell disease and cerebral malaria. Applications: Suitable for use in Function Blocking, Flow Cytometry, Immunofluorescence, and Immunohistochemistry. Not suitable for use in Western Blot. Other applications have not been tested. Recommended Dilution: Function Blocking: Order C2388-15X., Immunohistochemistry: Frozen, Optimal dilutions to be determined by the researcher. Positive Control: Tonsil, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.