Anti-CD357 [GITR] (human), clone ANC7D6, preservative free

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ANC-268-820	100 µg		-		3 - 9 business days*		301.00€

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Glucocorticoid induced TNF receptor family related gene (GITR, AITR) is a type 1 228 amino acid... more

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Product information "Anti-CD357 [GITR] (human), clone ANC7D6, preservative free"

Glucocorticoid induced TNF receptor family related gene (GITR, AITR) is a type 1 228 amino acid transmembrane protein that has been designated TNFRSF18. GITR is expressed mainly by CD4 CD25 T lymphocytes. Its engagement by antibodies or its ligand (GITRL) induces a costimulatory signal which can break T cell suppression. GITR has been implicated as a regulatory mechanism in anti-parasitic immune resposes, and is involved with macrophages activation in atherosclerotic plaque formation.

Keywords:	Anti-AITR, Anti-GITR, Anti-CD357, Anti-TNFRSF18, Anti-Activation-inducible TNFR family receptor, Anti-Glucocorticoid-induced TNFR-related protein, Anti-Tumor necrosis factor receptor superfamily member 18
Supplier:	Ancell
Supplier-Nr:	268-820

Properties

Application:	FC, ELISA
Antibody Type:	Monoclonal
Clone:	ANC7D6
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	Recombinant human GITR, PHA stimulated human PBL
Format:	Purified