Anti-CD30, clone SPM121

Anti-CD30, clone SPM121
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2991S-0.1ML 100 µl - -

3 - 10 business days*

332.00€
NSJ-V2991S-0.5ML 500 µl - -

3 - 10 business days*

752.00€
 
Bioreactor concentrate with 0.05% sodium azide. Recognizes a single chain glycoprotein of... more
Product information "Anti-CD30, clone SPM121"
Bioreactor concentrate with 0.05% sodium azide. Recognizes a single chain glycoprotein of 105/120kDa, identified as CD30/Ki-1. CD30 is synthesized as a 90kDa precursor, which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. In Hodgkin s disease, CD30/Ki-1 antigen is expressed by mononuclear-Hodgkin and multinucleated Reed-Sternberg cells. It is also expressed by the tumor cells of a majority of anaplastic large cell lymphomas as well as by a varying proportion of activated T and B cells. This mAb distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45). Protein function: Receptor for TNFSF8/CD30L. May play a role in the regulation of cellular growth and transformation of activated lymphoblasts. Regulates gene expression through activation of NF- kappa-B. [The UniProt Consortium]
Keywords: Anti-CD30, Anti-TNFRSF8, Anti-Ki-1 antigen, Anti-CD30L receptor, Anti-Lymphocyte activation antigen CD30, Anti-Tumor necrosis factor receptor superfamily member 8, CD30 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2991S

Properties

Application: FC, IF, IHC (paraffin)
Antibody Type: Monoclonal
Clone: SPM121
Conjugate: No
Host: Mouse
Species reactivity: human
Immunogen: Co cell line established from a patient with Hodgkins disease of T-cell lineage
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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