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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
C2254-56D.100 | 100 µg | - | - |
3 - 19 business days* |
698.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
These CD3 subunits are structurally related members of the immunoglobulins super family encoded... more
Product information "Anti-CD3 (CD3d, CD3e, CD3g, CD3z, Early T Cell Marker, T Cell Receptor Complex, TCR, T-cell Surface"
These CD3 subunits are structurally related members of the immunoglobulins super family encoded by closely linked genes on human chromosome 11. The CD3 components have long cytoplasmic tails that associate with cytoplasmic signal transduction molecules. This association is mediated at least in part by a double tyrosine-based motif present in a single copy in the CD3 subunits. CD3 may play a role in TCR-induced growth arrest, cell survival and proliferation. The CD3 antigen is present on 68-82% of normal peripheral blood lymphocytes, 65-85% of thymocytes and Purkinje cells in the cerebellum. It is never expressed on B or NK cells. Decreased percentages of T lymphocytes may be observed in some autoimmune diseases. Applications: Suitable for use in Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-T3E, Anti-CD3e, Anti-CD3E, Anti-T-cell surface glycoprotein CD3 epsilon chain, Anti-T-cell surface antigen T3/Leu-4 epsilon chain |
Supplier: | United States Biological |
Supplier-Nr: | C2254-56D |
Properties
Application: | IP |
Antibody Type: | Monoclonal |
Clone: | MEM-57 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human |
Immunogen: | Gene location: human chromosome 11q23. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K06451 | Matching products |
UniProt ID : | P07766 | Matching products |
Gene ID : | GeneID 916 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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