Anti-CD2AP

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA003326.25	25 µl		-		7 - 10 business days*		300.00€
ATA-HPA003326.100	100 µl		-		7 - 10 business days*		421.00€

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Protein function: Seems to act as an adapter protein between membrane proteins and the actin... more

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Product information "Anti-CD2AP"

Protein function: Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton (PubMed:10339567). In collaboration with CBLC, modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis (PubMed:15800069). Plays a role in epithelial cell junctions formation (PubMed:22891260). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 81% and to rat: 82%

Keywords:	Anti-CD2AP, Anti-Adapter protein CMS, Anti-CD2-associated protein, Anti-Cas ligand with multiple SH3 domains
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA003326

Properties

Application:	ICC, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: VDFDSLTVRT SKETDVVNFD DIASSENLLH LTANRPKMPG RRLPGRFNGG HSPTHSPEKI LKLPKEEDSA NLKPSELKKD TCYSPKPSVY LSTPSSASKA NTTAFLTPLE IKAKVETDDV KKNSLDELRA QIIELLCIVE ALKKDHGKEL (ATA-APrEST85224)