Anti-CD28 (human), clone ANC28.1/5D10

Anti-CD28 (human), clone ANC28.1/5D10
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ANC-177-020 100 µg -

3 - 9 business days*

209.00€
 
Human CD28 is an important costimulatory molecule found on all CD4 T cells and on about half of... more
Product information "Anti-CD28 (human), clone ANC28.1/5D10"
Human CD28 is an important costimulatory molecule found on all CD4 T cells and on about half of the CD8 T cells. T cell activities attributed to CD28 include prevention of anergy, induction of cytokine gene transcription, stabilization of cytokine mRNA and activation of CD8 cytotoxic T lymphocytes. The ligands for CD28 identified as CD80 (B7-1) and CD86 (B7-2) are immunglobulin superfamily monomeric transmembrane glycoproteins of 60kDa and 80kDa respectively. Anti-CD28 antibodies have been shown to have a strong adjuvant effect when conjugated to an immunogen. Monovalency of the CD28 receptor for its natural ligands is essential to provide costimulation without inducing responses in the absense of TCR engagement.
Keywords: Anti-TP44, Anti-CD28, Anti-T-cell-specific surface glycoprotein CD28
Supplier: Ancell
Supplier-Nr: ANC-177-020

Properties

Application: FC, ELISA
Antibody Type: Monoclonal
Clone: ANC28.1/5D10
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Recombinant Human CD28 and HPB-MLT human tumor cells
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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