Anti-CD28 (human), Azide Free Clone B-T3 [Mouse]

Specificity: Recognises the B7/BB1 receptor (B7/BB1 R), a 44 kDa protein, Format: Phosphate-buffered saline. Sterile-filtered through 0.22 µm. Carrier and preservative free, Storage: Store at +2-8°C for 12 months. For longer storage, freeze aliquots, Application Notes: Suitable for Flow Cytometry, IHC. Inhibits mixed lymphocyte culture. Co-stimulates T-cell proliferation Protein function: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037). [The UniProt Consortium]