Anti-CD28, clone 204.12

Anti-CD28, clone 204.12
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V2987-20UG 20 µg - -

3 - 10 business days

NSJ-V2987-100UG 100 µg - -

3 - 10 business days

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Recognizes a... more
Product information "Anti-CD28, clone 204.12"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Recognizes a glycoprotein of 44-88kDa, which is identified as CD28. It is the critical T-cell co-stimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its co-stimulation role, CD28 functions in preventing T-cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. CD28 is also expressed on human fetal NK cells and some NK cell lines, whereas on murine NK cells the CD28 expression is much broader. Protein function: Involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival. Enhances the production of IL4 and IL10 in T-cells in conjunction with TCR/CD3 ligation and CD40L costimulation (PubMed:8617933). Isoform 3 enhances CD40L-mediated activation of NF-kappa-B and kinases MAPK8 and PAK2 in T-cells (PubMed:15067037). [The UniProt Consortium]
Keywords: Anti-CD28, Anti-TP44, Anti-T-cell-specific surface glycoprotein CD28, CD28 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V2987-20UG


Application: FC, IF, FA (activity)
Antibody Type: Monoclonal
Clone: 204.12
Conjugate: No
Host: Mouse
Reactivity: Human, Swine, Bovine, Sheep, Mouse
Immunogen: Stimulated human leukocytes
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-CD28, clone 204.12"
Write a review
or to review a product.