Anti-CD278 / ICOS

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG58076.100	100 µl		-	-	6 - 14 business days*		624.00€

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Protein function: Enhances all basic T-cell responses to a foreign antigen, namely proliferation,... more

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Product information "Anti-CD278 / ICOS"

Protein function: Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up- regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up- regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre- activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes. [The UniProt Consortium]

Keywords:	Anti-ICOS, Anti-CD278, Anti-AILIM, Anti-Inducible T-cell costimulator, Anti-Activation-inducible lymphocyte immunomediatory molecule
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG58076

Properties

Application:	ICC, IF, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Recombinant funsion protein corresponding to aa. 21-140 of Human CD278 / ICOS (NP_036224.1)
MW:	22 kD
Format:	Affinity Purified